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Emtricitabine Enantiomer Impurity

Emtricitabine Enantiomer Impurity

Catalogue No.: VL54005
CAS No.: 137530-41-7

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Name: Emtricitabine Enantiomer Impurity
Catalogue No. VL54005
CAS No. 137530-41-7
Molecular Formula C8H10FN3O3S
Molecular Weight 247.25
Status In-stock
IUPAC Name 4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
Appearance Light Orange Powder
Description Emtricitabine Enantiomer Impurity (CAS No.137530-41-7) or 4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) in combination with other antiviral agents it shows activity against HIV. It is approved for the use in combination therapy.
References "Sax, Paul E., et al. “Coformulated Bictegravir, Emtricitabine, and Tenofovir Alafenamide versus Dolutegravir with Emtricitabine and Tenofovir Alafenamide, for Initial Treatment of HIV-1 Infection (GS-US-380–1490): A Randomised, Double-Blind, Multicentre, Phase 3, Non-Inferiority Trial.” The Lancet, vol. 390, no. 10107, Nov. 2017, pp. 2073–82, https://doi.org/10.1016/s0140-6736(17)32340-1. Bang, Lynne M., and Lesley J. Scott. “Emtricitabine.” Drugs, vol. 63, no. 22, 2003, pp. 2413–24, https://do

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