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Emtricitabine 5-Fluorouracil Analogue

Emtricitabine 5-Fluorouracil Analogue

Catalogue No.: VL54001
CAS No.: 143790-05-0

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Name: Emtricitabine 5-Fluorouracil Analogue
Catalogue No. VL54001
CAS No. 143790-05-0
Molecular Formula C8H9FN2O4S
Molecular Weight 248.23
Status In-stock
IUPAC Name 5-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolane-5-yl]uracil
Synonyms Emtricitabine Related Compound -1 / Emtricitabine Hydroxy Impurity
Appearance Light Orange powder
Description Emtricitabine 5-Fluorouracil Analogue or Emtricitabine Hydroxy Impurity (CAS No.‎143790-05-0) or 5-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolane-5-yl]uracil. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) in combination with other antiviral agents it shows activity against HIV. It is approved for the use in combination therapy.
References Bang, Lynne M., and Lesley J. Scott. “Emtricitabine.” Drugs, vol. 63, no. 22, 2003, pp. 2413–24, https://doi.org/10.2165/00003495-200363220-00003.Sax, Paul E., et al. “Coformulated Bictegravir, Emtricitabine, and Tenofovir Alafenamide versus Dolutegravir with Emtricitabine and Tenofovir Alafenamide, for Initial Treatment of HIV-1 Infection (GS-US-380–1490): A Randomised, Double-Blind, Multicentre, Phase 3, Non-Inferiority Trial.” The Lancet, vol. 390, no. 10107, Nov. 2017, pp. 2073–82, https://d

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