| Name: | Enalapril EP Impurity A |
| Catalogue No. | VL1360001 |
| CAS No. | 76420-74-1 |
| Molecular Formula | C20H27NO5 |
| Molecular Weight | 412.91 |
| Status | In-stock |
| IUPAC Name | (S)-1-((S)-2-(((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylic acid hydrochloride |
| Synonyms | (R,S,S)-Enalapril HCl / Enalapril HCl (1R)-Isomer |
| Description | Enalapril EP Impurity A or (R,S,S)-Enalapril HCl / Enalapril HCl (1R)-Isomer (CAS No.76420-74-1) or (S)-1-((S)-2-(((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylic acid hydrochloride. Enalapril is a prodrug that is hydrolyzed after absorption to form the active angiotensin-converting enzyme Enalaprilat. It is administered orally. It decreases blood pressure by lowering peripheral resistance without increasing heart rate. It is well tolerated and safe. |
| References | "Todd, Peter A., and Karen L. Goa. “Enalapril.” Drugs, vol. 43, no. 3, Mar. 1992, pp. 346–81, https://doi.org/10.2165/00003495-199243030-00005. Davies, Richard O., et al. “Enalapril Worldwide Experience.” The American Journal of Medicine, vol. 77, no. 2, Aug. 1984, pp. 23–35, https://doi.org/10.1016/s0002-9343(84)80055-8. " |
