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Enalapril EP Impurity A

Enalapril EP Impurity A

Catalogue No.: VL1360001
CAS No.: 76420-74-1

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Name: Enalapril EP Impurity A
Catalogue No. VL1360001
CAS No. 76420-74-1
Molecular Formula C20H27NO5
Molecular Weight 412.91
Status In-stock
IUPAC Name (S)-1-((S)-2-(((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylic acid hydrochloride
Synonyms (R,S,S)-Enalapril HCl / Enalapril HCl (1R)-Isomer
Description Enalapril EP Impurity A or (R,S,S)-Enalapril HCl / Enalapril HCl (1R)-Isomer (CAS No.76420-74-1) or (S)-1-((S)-2-(((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylic acid hydrochloride. Enalapril is a prodrug that is hydrolyzed after absorption to form the active angiotensin-converting enzyme Enalaprilat. It is administered orally. It decreases blood pressure by lowering peripheral resistance without increasing heart rate. It is well tolerated and safe.
References "Todd, Peter A., and Karen L. Goa. “Enalapril.” Drugs, vol. 43, no. 3, Mar. 1992, pp. 346–81, https://doi.org/10.2165/00003495-199243030-00005. ‌Davies, Richard O., et al. “Enalapril Worldwide Experience.” The American Journal of Medicine, vol. 77, no. 2, Aug. 1984, pp. 23–35, https://doi.org/10.1016/s0002-9343(84)80055-8. ‌"

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