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Entacapone EP Impurity E

Entacapone EP Impurity E

Catalogue No.: VL2400004
CAS No.: 7659-29-2

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Name: Entacapone EP Impurity E
Catalogue No. VL2400004
CAS No. 7659-29-2
Molecular Formula C6H4N2O6
Molecular Weight 200.11
Status In-stock
IUPAC Name 3,5-Dinitro-pyrocatechol
Appearance Yellow Powder
Description Entacapone EP Impurity E (CAS No.7659-29-2) or 3,5-Dinitro-pyrocatechol. Entacapone is a potent and specific peripheral catechol-o-methyltransferase inhibitor (COMT) inhibitor. It is used in the treatment of parkinsons disease.The Z isomer of entacapone is the important metabolite in human plasma.
References "Holm, Kristin J., and Caroline M. Spencer. “Entacapone.” Drugs, vol. 58, no. 1, 1999, pp. 159–77, https://doi.org/10.2165/00003495-199958010-00017. ‌Schrag, Anette. “Entacapone in the Treatment of Parkinson’s Disease.” The Lancet Neurology, vol. 4, no. 6, June 2005, pp. 366–70, https://doi.org/10.1016/s1474-4422(05)70098-3. ‌"

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