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Entacapone Methoxy Impurity

Entacapone Methoxy Impurity

Catalogue No.: VL2400013
CAS No.: 857629-78-8

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Name: Entacapone Methoxy Impurity
Catalogue No. VL2400013
CAS No. 857629-78-8
Molecular Formula C15H17N3O5
Molecular Weight 319.31
Status In-stock
IUPAC Name (2E)-2-Cyano-3-(3-methoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
Appearance Yellow Color Powder
Description Entacapone Methoxy Impurity (CAS No.857629-78-8) or (2E)-2-Cyano-3-(3-methoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide. Entacapone is a potent and specific peripheral catechol-o-methyltransferase inhibitor (COMT) inhibitor. It is used in the treatment of parkinsons disease.The Z isomer of entacapone is the important metabolite in human plasma.
References "Holm, Kristin J., and Caroline M. Spencer. “Entacapone.” Drugs, vol. 58, no. 1, 1999, pp. 159–77, https://doi.org/10.2165/00003495-199958010-00017. ‌Schrag, Anette. “Entacapone in the Treatment of Parkinson’s Disease.” The Lancet Neurology, vol. 4, no. 6, June 2005, pp. 366–70, https://doi.org/10.1016/s1474-4422(05)70098-3. ‌"

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