
Name: | Entacapone N N Diethyl Cyanoacetamide |
Catalogue No. | VL2400011 |
CAS No. | N/A |
Molecular Formula | C7H12N20 |
Molecular Weight | 140.18 |
Status | In-stock |
IUPAC Name | 2-cyano-N, N-Diethylacetamide |
Description | Entacapone N N Diethyl Cyanoacetamide or 2-cyano-N, N-Diethylacetamide. Entacapone is a potent and specific peripheral catechol-o-methyltransferase inhibitor (COMT) inhibitor. It is used in the treatment of parkinsons disease.The Z isomer of entacapone is the important metabolite in human plasma. |
References | "Holm, Kristin J., and Caroline M. Spencer. “Entacapone.” Drugs, vol. 58, no. 1, 1999, pp. 159–77, https://doi.org/10.2165/00003495-199958010-00017. Schrag, Anette. “Entacapone in the Treatment of Parkinson’s Disease.” The Lancet Neurology, vol. 4, no. 6, June 2005, pp. 366–70, https://doi.org/10.1016/s1474-4422(05)70098-3. " |