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Etoricoxib Inhouse Impurity E

Etoricoxib Inhouse Impurity E

Catalogue No.: VL1020005
CAS No.: 5470-70-2

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Name: Etoricoxib Inhouse Impurity E
Catalogue No. VL1020005
CAS No. 5470-70-2
Molecular Formula C₈H₉NO₂
Molecular Weight 151.16
Status In-stock
IUPAC Name 6-Methyl-3-pyridinecarboxylic Acid Methyl Ester
Synonyms Methyl 6-methylnicotinate
Description Methyl 6-Methylnicotinate or Etoricoxib Impurity E (CAS No: 5470-70-2) is used in the synthesis of 6-(2-Phenylethyl)nicotine that is a novel nicotinic cholinergic receptor ligand. It is also used as a starting material in the synthesis of Dimebon and of its Tetrathiomolybdate. Dimebon is a non-selective antihistamine that displays cognitive enhancing abilities and does not inhibit acetylcholinesterase activity.
References Ramunno, Anna, et al. “6-(2-Phenylethyl)Nicotine: A Novel Nicotinic Cholinergic Receptor Ligand.” Bioorganic & Medicinal Chemistry Letters, vol. 15, no. 13, July 2005, pp. 3237–40, https://doi.org/10.1016/j.bmcl.2005.04.072.

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