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Ezetimibe SRS Impurity

Ezetimibe SRS Impurity

Catalogue No.: VL203001
CAS No.: N/A

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Name: Ezetimibe SRS Impurity
Catalogue No. VL203001
CAS No. N/A
Molecular Formula C24H21F2NO3
Molecular Weight 409.43
Status In-stock
IUPAC Name (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Description Ezetimibe SRS Impurity (CAS No: 1593543-00-0) is a process-related impurity. Ezetimibe is a potent cholesterol absorption inhibitor. It strongly blocks the absorption of biliary and dietary cholesterol from the small intestine. It is evaluated for the treatment of primary hypercholesterolemia, homozygous sitosterolemia, homozygous familial hypercholesterolemia (HoFH), and mixed hyperlipidemia.
References Filip, Katarzyna, et al. “Physicochemical Characterization of Ezetimibe and Its Impurities.” Journal of Molecular Structure, vol. 991, no. 1-3, Apr. 2011, pp. 162–70, https://doi.org/10.1016/j.molstruc.2011.02.020.

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