| Name: | Fluoro Desloratadine |
| Catalogue No. | VL41008 |
| CAS No. | 298220-99-2 |
| Molecular Formula | C₁₉H₂₀ClFN₂ |
| Molecular Weight | 330.83 |
| Status | In-stock |
| IUPAC Name | 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine |
| Description | Fluoro Desloratadine (CAS No.: 298220-99-2) or 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine is a fluoro derivative of Desloratadine which is a selective H1-receptor inhibitor and also depicts anti-inflammatory activity. Desloratadine blocks the release of multiple inflammatory mediators IL-4, IL-6, IL-8, IL-13, PGD2. |
| References | Zheng, Jinjian, and Abu M. Rustum. “Rapid Separation of Desloratadine and Related Compounds in Solid Pharmaceutical Formulation Using Gradient Ion-Pair Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 1, Jan. 2010, pp. 146–52,https://doi.org/10.1016/j.jpba.2009.08.024.Geha, Raif S., and Eli O. Meltzer. “Desloratadine: A New, Nonsedating, Oral Antihistamine.” Journal of Allergy and Clinical Immunology, vol. 107, no. 4, Apr. 2001, pp. 751–62,https://doi.org/10.1067 |
