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Gefitinib Impurity 12

Gefitinib Impurity 12

Catalogue No.: VL4010007
CAS No.: 184475-71-6

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Name: Gefitinib Impurity 12
Catalogue No. VL4010007
CAS No. 184475-71-6
Molecular Formula C15H11ClFN3O2
Molecular Weight 319.72
Status In-stock
IUPAC Name 4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol
Synonyms O-Desmorpholinopropyl Gefitinib
Appearance Off White Powder
Description Gefitinib Impurity 12 ( CAS No: 184475-71-6 ) or 4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol is a process impurity of Gefitinib which is a selective tyrosine kinase receptor inhibitor used in the therapy of non-small cell lung cancer.
References Cohen, Martin H., et al. “FDA Drug Approval Summary: Gefitinib (ZD1839) (Iressa ® ) Tablets.” The Oncologist, vol. 8, no. 4, Aug. 2003, pp. 303–6, https://doi.org/10.1634/theoncologist.8-4-303.

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