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Lansoprazole EP Impurity D

Lansoprazole EP Impurity D

Catalogue No.: VL92009
CAS No.: 615-16-7

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Name: Lansoprazole EP Impurity D
Catalogue No. VL92009
CAS No. 615-16-7
Molecular Formula C7H6N2O
Molecular Weight 134.14
Status In-stock
IUPAC Name 1H-Benzimidazol-2-ol
Synonyms 1H-Benzimidazol-2-ol/2-Hydroxybenzimidazole
Description Lansoprazole EP Impurity D (CAS No: 615-16-7) or 2-Hydroxybenzimidazole chemically known as 1H-Benzimidazol-2-ol is an impurity formed during the synthesis of Lansoprazole that is a potent non-reversible gastric proton pump H+/K+-ATPase inhibitor, that is responsible for gastric acid secretion it is therefore used to treat and prevent gastrointestinal ulcers and gastroesophageal reflux disease.
References Cirilli, Roberto, et al. “Development and Validation of an Enantioselective and Chemoselective HPLC Method Using a Chiralpak IA Column to Simultaneously Quantify (R)-(+)- and (S)-(−)-Lansoprazole Enantiomers and Related Impurities.” Journal of Pharmaceutical and Biomedical Analysis, vol. 50, no. 1, Aug. 2009, pp. 9–14, https://doi.org/10.1016/j.jpba.2009.03.021.

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