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Metoprolol EP Impurity D

Metoprolol EP Impurity D

Catalogue No.: VL103007
CAS No.: 62572-90-1

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Name: Metoprolol EP Impurity D
Catalogue No. VL103007
CAS No. 62572-90-1
Molecular Formula C₁₂H₁₈O₄
Molecular Weight 226.27
Status In-stock
IUPAC Name (2RS)-3-[4-(2-Methoxyethyl)phenoxy]propane-1,2-diol
Appearance Colorless Liquid
Description Metoprolol EP Impurity D (CAS No: 62572-90-1) is an impurity present in metoprolol which is broadly used in the treatment of essential hypertension, diabetes mellitus, obesity, ischaemic heart disease, heart failure, arrhythmias, secondary hypertension, acute or chronic inflammatory disease, and hypercholesterolemia.
References Erickson, Magnus, et al. “Identification of a New By-Product Detected in Metoprolol Tartrate.” Journal of Pharmaceutical and Biomedical Analysis, vol. 13, no. 4-5, Apr. 1995, pp. 567–74, https://doi.org/10.1016/0731-7085(95)01277-r. “Nebivolol and Metoprolol: Long-Term Effects on Inflammation and Oxidative Stress in Essential Hypertension.” Scandinavian Journal of Clinical and Laboratory Investigation, 2012, www.tandfonline.com/doi/abs/10.3109/00365513.2012.691991.

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