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Metoprolol EP Impurity E

Metoprolol EP Impurity E

Catalogue No.: VE006518
CAS No.: 163685-38-9

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Name: Metoprolol EP Impurity E
Catalogue No. VE006518
CAS No. 163685-38-9
Molecular Formula C15H25NO3
Molecular Weight 267.36
Status In-stock
IUPAC Name (2RS)-1-[2-(2-Methoxyethyl)phenoxy]- 3-[(1-methylethyl)amino]propan-2-ol
Description Metoprolol EP Impurity E (CAS No: 163685-38-9) is an impurity present in the synthesis of Metoprolol is used for the treatment of angina, heart failure, myocardial infarction, atrial fibrillation/flutter, and hypertension. It has demonstrated prognostic advantage and lessens mortality in the treatment of chronic heart failure.
References Erickson, Magnus, et al. “Identification of a New By-Product Detected in Metoprolol Tartrate.” Journal of Pharmaceutical and Biomedical Analysis, vol. 13, no. 4-5, Apr. 1995, pp. 567–574, www.sciencedirect.com/science/article/abs/pii/073170859501277R, 10.1016/0731-7085(95)01277-r. Accessed 27 Sept. 2021. Morris J, Dunham A. Metoprolol. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2020. PMID: 30422518. https://europepmc.org/article/NBK/nbk532923

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