| Name: | Metoprolol EP Impurity F |
| Catalogue No. | VL103013 |
| CAS No. | 7695-63-8 |
| Molecular Formula | C₁₂H₁₉NO₂ |
| Molecular Weight | 209.28 |
| Status | In-stock |
| IUPAC Name | (2RS)-1-[(1-Methylethyl)amino]-3-phenoxypropan-2-ol |
| Synonyms | Metoprolol Succinate EP Impurity F/ Metoprolol Tartarate EP Impurity F |
| Appearance | White to Off white Solid powder |
| Description | Metoprolol EP Impurity F (CAS No: 7695-63-8) or Metoprolol Succinate EP Impurity F/ Metoprolol Tartarate EP Impurity F (1-Isopropylamino-3-phenoxypropan-2-ol) is an impurity present in metoprolol which is of therapeutic value in the treatment of various cardiovascular disorders, such as angina pectoris, cardiac arrhythmia. Physicochemical nature shows a membrane-stabilizing effect, a local anesthetic action as well as a cardio depressant effect. |
| References | Erickson, Magnus, et al. “Identification of a New By-Product Detected in Metoprolol Tartrate.” Journal of Pharmaceutical and Biomedical Analysis, vol. 13, no. 4-5, Apr. 1995, pp. 567–74, https://doi.org/10.1016/0731-7085(95)01277-r. Winkler, Horst, et al. “High-Performance Liquid Chromatographic Method for the Quantitative Analysis of the Aryloxypropanolamines Propranolol, Metoprolol and Atenolol in Plasma and Tissue.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 228, |
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