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Metoprolol EP Impurity J

Metoprolol EP Impurity J

Catalogue No.: VL103016
CAS No.: 163685-37-8

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Name: Metoprolol EP Impurity J
Catalogue No. VL103016
CAS No. 163685-37-8
Molecular Formula C₁₈H₃₁NO₅
Molecular Weight 341.44
Status In-stock
IUPAC Name 1-[2-Hydroxy-3-[(1-methylethyl) amino]propoxy]-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
Appearance Brown Sticky Liquid
Description Metoprolol EP Impurity J (CAS No: 163685-37-8) is an impurity present in metoprolol which has demonstrated prognostic advantage and lessens mortality in the treatment of chronic heart failure. Also, it is extensively used for the treatment of angina, chest pain, high blood pressure, and acute myocardial infarction.
References Erickson, Magnus, et al. “Identification of a New By-Product Detected in Metoprolol Tartrate.” Journal of Pharmaceutical and Biomedical Analysis, vol. 13, no. 4-5, Apr. 1995, pp. 567–74, https://doi.org/10.1016/0731-7085(95)01277-r. Morris J, Dunham A. Metoprolol. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2020. PMID: 30422518. https://europepmc.org/article/NBK/nbk532923

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