
Name: | Metoprolol EP Impurity J |
Catalogue No. | VL103016 |
CAS No. | 163685-37-8 |
Molecular Formula | C₁₈H₃₁NO₅ |
Molecular Weight | 341.44 |
Status | In-stock |
IUPAC Name | 1-[2-Hydroxy-3-[(1-methylethyl) amino]propoxy]-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol |
Appearance | Brown Sticky Liquid |
Description | Metoprolol EP Impurity J (CAS No: 163685-37-8) is an impurity present in metoprolol which has demonstrated prognostic advantage and lessens mortality in the treatment of chronic heart failure. Also, it is extensively used for the treatment of angina, chest pain, high blood pressure, and acute myocardial infarction. |
References | Erickson, Magnus, et al. “Identification of a New By-Product Detected in Metoprolol Tartrate.” Journal of Pharmaceutical and Biomedical Analysis, vol. 13, no. 4-5, Apr. 1995, pp. 567–74, https://doi.org/10.1016/0731-7085(95)01277-r. Morris J, Dunham A. Metoprolol. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2020. PMID: 30422518. https://europepmc.org/article/NBK/nbk532923 |