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Metoprolol Hydroxy Epoxide Impurity

Metoprolol Hydroxy Epoxide Impurity

Catalogue No.: VL103017
CAS No.: 104857-48-9

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Name: Metoprolol Hydroxy Epoxide Impurity
Catalogue No. VL103017
CAS No. 104857-48-9
Molecular Formula C11H14O3
Molecular Weight 194.23
Status In-stock
IUPAC Name 4-(2-Oxiranylmethoxy)benzeneethanol
Synonyms Metoprolol Epoxy Hydroxyethyl Impurity
Appearance Light yellow powder
Description Metoprolol Hydroxy Epoxide Impurity (CAS No: 104857-48-9) is an impurity used in the synthesis of metoprolol which competitively inhibits the effects of catecholamines at beta-adrenergic receptors and has a diverse range of clinical applications in the treatment of cardiovascular disorders.
References Muthukrishnan, M., et al. “Concise Synthesis of β-Blockers (S)-Metoprolol and (S)-Betaxolol Using Hydrolytic Kinetic Resolution.” Tetrahedron, vol. 63, no. 8, Feb. 2007, pp. 1872–76, https://doi.org/10.1016/j.tet.2006.12.016.

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