
Name: | Metoprolol Hydroxy Epoxide Impurity |
Catalogue No. | VL103017 |
CAS No. | 104857-48-9 |
Molecular Formula | C11H14O3 |
Molecular Weight | 194.23 |
Status | In-stock |
IUPAC Name | 4-(2-Oxiranylmethoxy)benzeneethanol |
Synonyms | Metoprolol Epoxy Hydroxyethyl Impurity |
Appearance | Light yellow powder |
Description | Metoprolol Hydroxy Epoxide Impurity (CAS No: 104857-48-9) is an impurity used in the synthesis of metoprolol which competitively inhibits the effects of catecholamines at beta-adrenergic receptors and has a diverse range of clinical applications in the treatment of cardiovascular disorders. |
References | Muthukrishnan, M., et al. “Concise Synthesis of β-Blockers (S)-Metoprolol and (S)-Betaxolol Using Hydrolytic Kinetic Resolution.” Tetrahedron, vol. 63, no. 8, Feb. 2007, pp. 1872–76, https://doi.org/10.1016/j.tet.2006.12.016. |