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Mirabegron Impurity C

Mirabegron Impurity C

Catalogue No.: VL3070003
CAS No.: 521284-22-0

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Name: Mirabegron Impurity C
Catalogue No. VL3070003
CAS No. 521284-22-0
Molecular Formula C16H20N2O
Molecular Weight 256.34
Status In-stock
IUPAC Name (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol
Description Mirabegron Impurity C (CAS No. 521284-22-0) is an impurity present in mirabegron which is a β3-adrenoceptor subtype that is the predominant form of β-adrenoceptor in the bladder. Its stimulation is associated with increased bladder capacity without a change in micturition pressure, PVR, or voiding contraction.
References Takusagawa, Shin, et al. “Absorption, Metabolism and Excretion of [14C]Mirabegron (YM178), a Potent and Selective β3-Adrenoceptor Agonist, after Oral Administration to Healthy Male Volunteers.” Drug Metabolism and Disposition, vol. 40, no. 4, Jan. 2012, pp. 815–24, https://doi.org/10.1124/dmd.111.043588. Nitti, Victor W., et al. “Urodynamics and Safety of the β 3 -Adrenoceptor Agonist Mirabegron in Males with Lower Urinary Tract Symptoms and Bladder Outlet Obstruction.” Journal of Urology, vol.

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