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Mometasone Furoate Impurity M

Mometasone Furoate Impurity M

Catalogue No.: VL4080010
CAS No.: 57780-86-6

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Name: Mometasone Furoate Impurity M
Catalogue No. VL4080010
CAS No. 57780-86-6
Molecular Formula C₂₂H₂₉ClO₄
Molecular Weight 392.92
Status In-stock
IUPAC Name (11β,16α)-9-Chloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione
Description Mometasone Furoate Impurity M (CAS No: 57780-86-6) is an impurity present in the synthesis of mometasone which is a synthetic corticosteroid that has been evaluated to inhibit the influx of inflammatory cells to the nasal mucosa in adults and children with allergic rhinitis. It is used for the medication of perennial allergic rhinitis in patients with moderate to severe symptoms.
References Das, Saibal Kumar, et al. “Improvements in Corticosteroid 21-Acetoxy-17α-Hydroxy-16α-Methyl-Pregna-1,4,9(11)-Triene-3,20-Dione Synthesis and Its Use as Common Intermediate in the Synthesis of Some Impurities Related to Dexamethasone and Mometasone.” Steroids, vol. 148, Aug. 2019, pp. 47–55, https://doi.org/10.1016/j.steroids.2019.04.008. ‌Onrust, Susan V., and Harriet M. Lamb. “Mometasone Furoate.” Drugs, vol. 56, no. 4, 1998, pp. 725–45, https://doi.org/10.2165/00003495-199856040-00018.

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