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Montelukast Nitrile Impurity

Montelukast Nitrile Impurity

Catalogue No.: VL510004
CAS No.: 866923-62-8

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Name: Montelukast Nitrile Impurity
Catalogue No. VL510004
CAS No. 866923-62-8
Molecular Formula C₃₅H₃₅ClN₂OS
Molecular Weight 567.18
Status In-stock
IUPAC Name :1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetonitrile
Description Montelukast Nitrile Impurity (CAS No: 866923-62-8) is an impurity present in the synthesis of montelukast which is used as an effective and well-tolerated oral treatment for allergic airway inflammation in patients with SAR or PAR without asthma.
References “New and Practical Synthesis of Montelukast Sodium, an Antiasthmatic Drug.” Synthetic Communications, 2013, www.tandfonline.com/doi/abs/10.1080/00397911.2012.684755. ‌Nayak, Anjuli, and Ronald B. Langdon. “Montelukast in the Treatment of Allergic Rhinitis.” Drugs, vol. 67, no. 6, 2007, pp. 887–901, https://doi.org/10.2165/00003495-200767060-00005. ‌

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