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Montelukast Sulfone Impurity

Montelukast Sulfone Impurity

Catalogue No.: VL510021
CAS No.: 1266620-74-9

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Name: Montelukast Sulfone Impurity
Catalogue No. VL510021
CAS No. 1266620-74-9
Molecular Formula C₃₅H₃₆ClNO₅S
Molecular Weight 618.18
Status In-stock
IUPAC Name 1-[[[1-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfonyl]methyl]cyclopropaneacetic Acid;
Description Montelukast Sulfone Impurity (CAS No: 1266620-74-9) is an impurity present in montelukast which is used for allergic rhinitis and hives of long duration. It belongs to the quinoline series. It is a curative agent for the medication of bronchial asthma and second-line treatment of allergic rhinitis(AR).
References Emerce, Esra, et al. “Determination of the Impurities in Drug Products Containing Montelukast and in Silico/in Vitro Genotoxicological Assessments of Sulfoxide Impurity.” Toxicology Letters, vol. 238, no. 2, Oct. 2015, pp. 90–99, https://doi.org/10.1016/j.toxlet.2015.07.003. ‌Pandey, Lawanya, et al. A REVIEW on TOXICOLOGICAL STUDY of MONTELUKAST. www.ijramr.com/sites/default/files/issues-pdf/3731.pdf. Accessed 5 Oct. 2021. ‌

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