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Montelukast Sulphoxide Impurity

Montelukast Sulphoxide Impurity

Catalogue No.: VL510006
CAS No.: N/A

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Name: Montelukast Sulphoxide Impurity
Catalogue No. VL510006
Molecular Formula C35H36ClNO4S
Molecular Weight 602.18
Status In-stock
IUPAC Name 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfinylmethyl]cyclopropyl]acetic Acid
Synonyms Montelukast USP Related Compound C/ Montelukast Sulfoxid/Montelukast EP Impurity C/Montelukast Related Compound A
Appearance Off white powder
Description Montelukast Sulphoxide Impurity (CAS No: 909849-96-3) is an impurity present in montelukast which is an effective cysteinyl leukotriene (cysLT) receptor antagonist that protected against mouse BPD induced by hyperoxia thereby inhibiting inflammation, oxidative stress, and lung cell apoptosis.
References Barnabas, K. Samuel, et al. “A Novel Stability-Indicating Method for Determination of Related Substances of Montelukast Sodium in a Pharmaceutical Dosage Form Using RP-HPLC.” Chromatographia, vol. 84, no. 7, June 2021, pp. 645–62, https://doi.org/10.1007/s10337-021-04045-8. ‌Chen, Xin, et al. “Effect of Montelukast on Bronchopulmonary Dysplasia (BPD) and Related Mechanisms.” Medical Science Monitor, vol. 25, Mar. 2019, pp. 1886–93, https://doi.org/10.12659/msm.912774. ‌

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