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N-Nitroso Desloratadine

N-Nitroso Desloratadine

Catalogue No.: VE007389
CAS No.: 1246819-22-6

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Name: N-Nitroso Desloratadine
Catalogue No. VE007389
CAS No. 1246819-22-6
Molecular Formula C19H18ClN3O
Molecular Weight 339.82 g/mol
Status In-Stock
IUPAC Name 8-Chloro-6,11-dihydro-11-(1-nitroso-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Description N-Nitroso Desloratadine (CAS No.: 1246819-22-6) or 8-Chloro-6,11-dihydro-11-(1-nitroso-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine is biotransformation of Desloratadine which is an orally potent peripheral histamine H1-receptor inhibitor and doesn't have any sedative properties and is also evaluated for the treatment of seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR) and chronic idiopathic urticaria (CIU).
References Brambilla, Giovanni, et al. “Genotoxicity and Carcinogenicity Studies of Antihistamines.” Archives of Toxicology, vol. 85, no. 10, Feb. 2011, pp. 1173–87,https://doi.org/10.1007/s00204-011-0659-4.‌Murdoch, David, et al. “Desloratadine.” Drugs, vol. 63, no. 19, 2003, pp. 2051–77,https://doi.org/10.2165/00003495-200363190-00010.‌

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