| Name: | N-Nitroso Desloratadine |
| Catalogue No. | VE007389 |
| CAS No. | 1246819-22-6 |
| Molecular Formula | C19H18ClN3O |
| Molecular Weight | 339.82 g/mol |
| Status | In-Stock |
| IUPAC Name | 8-Chloro-6,11-dihydro-11-(1-nitroso-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine |
| Description | N-Nitroso Desloratadine (CAS No.: 1246819-22-6) or 8-Chloro-6,11-dihydro-11-(1-nitroso-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine is biotransformation of Desloratadine which is an orally potent peripheral histamine H1-receptor inhibitor and doesn't have any sedative properties and is also evaluated for the treatment of seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR) and chronic idiopathic urticaria (CIU). |
| References | Brambilla, Giovanni, et al. “Genotoxicity and Carcinogenicity Studies of Antihistamines.” Archives of Toxicology, vol. 85, no. 10, Feb. 2011, pp. 1173–87,https://doi.org/10.1007/s00204-011-0659-4.Murdoch, David, et al. “Desloratadine.” Drugs, vol. 63, no. 19, 2003, pp. 2051–77,https://doi.org/10.2165/00003495-200363190-00010. |
