| Name: | Nebivolol RRRR |
| Catalogue No. | VL490020 |
| CAS No. | N/A |
| Molecular Formula | C22H25F2NO9 |
| Molecular Weight | 405.43 |
| Status | In-stock |
| IUPAC Name | (R,1R,1’R)-2-2’azanediylbis(1-( R)-6-flurochroman-2-yl)ethanol |
| Description | Nebivolol RRRR is an impurity present in Nebivolol which is a cardioselective β-blocker that has been reported to be efficacious and well-tolerated for achieving BP control in patients with hypertension. Preliminary evidence suggests a potential for reduced mortality in patients with heart failure. |
| References | Chandrasekhar, S. “Enantioselective Total Synthesis of the Antihypertensive Agent (S,R,R,R)-Nebivolol.” Tetrahedron, vol. 56, no. 34, Aug. 2000, pp. 6339–44,https://doi.org/10.1016/s0040-4020(00)00572-x.Cheng, Judy W. M. “Nebivolol: A Third-Generation β-Blocker for Hypertension.” Clinical Therapeutics, vol. 31, no. 3, Mar. 2009, pp. 447–62,https://doi.org/10.1016/j.clinthera.2009.03.007. |
