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(S,R,R)-Aprepitant

(S,R,R)-Aprepitant

Catalogue No.: VE006982
CAS No.: 1242175-34-3

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Name: (S,R,R)-Aprepitant
Catalogue No. VE006982
CAS No. 1242175-34-3
Molecular Formula C₂₃H₂₁F₇N₄O₃
Molecular Weight 534.43
Status In-Stock
IUPAC Name 5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
Description (S, R,R)-Aprepitant (CAS NO.-1242175-34-3) IUPAC Name-5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Aprepitant belongs to the neurokinin NK1 receptor antagonists class of agents. it is given in combination with other agents in order to prevent acute and delayed chemotherapy-induced nausea and vomiting (CINV) associated with highly emetogenic chemotherapy in adults. aprepitant (125mg day 1, 80mg days 2 an
References Dando, Toni M., and Caroline M. Perry. “Aprepitant.” Drugs, vol. 64, no. 7, 2004, pp. 777–94, https://doi.org/10.2165/00003495-200464070-00013. Curran, Monique P., and Dean M. Robinson. “Aprepitant.” Drugs, vol. 69, no. 13, Sept. 2009, pp. 1853–78, https://doi.org/10.2165/11203680-000000000-00000.

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